Guide
Generic medicines — myths and facts
Prepared by the LekCheck team · Last reviewed: 2026-07-25 · How we create our content
Generic medicines are often significantly cheaper than the original brand, which raises doubts about whether they are just as good. Below we dispel the common myths and explain the facts — what a generic is, why it is cheaper and when there may be a difference. The aim is to help you choose informed; for a specific medicine, always consult a doctor or pharmacist.
This guide was prepared by the LekCheck team and has not been reviewed by a doctor or pharmacist. This article is for general information only and is not medical advice, diagnosis, or treatment. Do not start, stop, or change any treatment without consulting a doctor or pharmacist.
What a generic medicine is
A generic medicine contains the same active ingredient, in the same dose and form as the original (reference) medicine, and is used for the same indications. It is authorised after the original no longer has patent protection, and must prove that it works the same way (bioequivalence). So generics are not 'weaker' versions.
Why generics are cheaper
Generic medicines are cheaper mainly because their manufacturer does not bear the cost of the initial development and clinical trials of the active ingredient — those were already done for the original. The lower price does not mean lower quality: generics are made to the same quality standards and are controlled by the regulator.
Are there real differences
The active ingredient is the same, but the excipients (fillers, colourings, the tablet form) may differ. For most people this does not matter, but rarely someone may react to a certain excipient or prefer a particular form. If you notice a difference when switching, tell the pharmacist or doctor.
When to consult
For most conditions, a generic and the original are interchangeable. With narrow dosing margins (e.g. certain thyroid, epilepsy or blood-clotting medicines), it is sensible for the switch to be made on medical judgement. For questions about which product suits you, ask a doctor or pharmacist.
Frequently asked questions
Are generic medicines weaker than the originals?
No. A generic medicine contains the same active ingredient in the same dose and must prove that it works the same way as the original (bioequivalence). The lower price comes from saved development costs, not from lower quality or a weaker effect.
Why is the generic so much cheaper?
Because the generic's manufacturer does not bear the cost of the initial discovery and clinical trials of the active ingredient — those were already done for the original. In addition, competition between several generics lowers the price. Quality is controlled to the same regulatory standards.
Is it safe to switch the original for a generic?
For most medicines yes — they are interchangeable. For some medicines with a narrow therapeutic margin, the switch is best made on medical judgement. If after switching you notice a change in effect or tolerability, tell the doctor or pharmacist.
Does the generic's composition differ?
The active ingredient is the same, but the excipients (e.g. fillers, colourings, the form) may differ between products. For most people this does not matter, but with a known allergy or intolerance to an excipient, check the composition or ask a pharmacist.
How do I find a cheaper generic?
Look for medicines with the same active ingredient and dose — there are often several products at different prices. LekCheck shows alternatives by active ingredient and prices from different pharmacies. Whether a specific product suits you is judged by the doctor and pharmacist.